Dobrava-Belgrade virus causes the most severe form of HFRS in Europe, with case fatality approaching that of East Asian Hantaan virus. It is endemic across the Balkans with sporadic outbreaks tied to rodent population cycles, and has been responsible for cluster events in Slovenia, Bosnia and Greece.
| Reservoir host | Yellow-necked mouse (Apodemus flavicollis) and others |
| Geographic range | Balkans (Slovenia, Bosnia, Serbia, Albania, Greece), parts of Russia and Estonia |
| Disease syndrome | Severe hemorrhagic fever with renal syndrome |
| Case fatality rate | ~10-12% |
| Vaccine | None licensed in most countries |
| Specific treatment | None. Supportive care. |
Dobrava-Belgrade virus causes the most severe form of HFRS in Europe, with case fatality approaching that of East Asian Hantaan virus. It is endemic across the Balkans with sporadic outbreaks tied to rodent population cycles, and has been responsible for cluster events in Slovenia, Bosnia and Greece.